This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract. Key outcomes include best-corrected visual acuity, stereopsis, refractive error, and axial length growth. The study will help identify long-term trends and prognostic indicators after early cataract intervention in pediatric patients.
Study Type
OBSERVATIONAL
Enrollment
400
Eye and ENT hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGVisual Acuity
UDVA and BCVA will be assessed using age-appropriate optotypes (e.g., Snellen chart, ETDRS chart, or Lea symbols) and recorded in logMAR units at the last available follow-up, with a minimum duration of 5 years postoperatively.
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
axial length
AL
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Refractive Error
Refractive Error
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
IOP
intraocular pressure
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Corneal Curvature (K1 and K2) by Pentacam
Flat (K1) and steep (K2) corneal curvature values will be measured using Pentacam and recorded in diopters (D).
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Stereopsis
Stereopsis will be assessed using age-appropriate tools (e.g., Randot Preschool or Titmus Fly Test) and reported in seconds of arc. Loss of stereopsis is defined as \>3000 arcsec.
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
white to white
WTW (mm)
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
anterior chamber depth
ACD(mm)
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Complications
Any postoperative complications following congenital cataract surgery, including glaucoma, anterior capsular opacification (ACO), etc.
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Central Corneal Thickness (CCT)
Corneal pachymetry will be measured with Pentacam at the central point and reported in microns (µm).
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Corneal Astigmatism Magnitude
Corneal astigmatism will be calculated from the difference between steep and flat meridians (K2-K1) using Pentacam data, and reported in diopters.
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.
Binocular Fusion Assessment
Binocular fusion will be evaluated using the Worth 4-Dot test under near and distance conditions. Results will be categorized as "fusion", "suppression", or "alternation".
Time frame: Participants will be followed at 1 week, 1 month, 3 months, 6 months, and annually from 1 to 5 years postoperatively.