Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using data from the Korean National Health Insurance Service (K-NHIS) database to evaluate the impact of regular physical activity.
It is well established that patients with T2DM and abdominal obesity have worse clinical outcomes. This holds true even among individuals with a normal body weight but central (abdominal) obesity. In this study, the investigators aimed to determine whether engaging in regular physical activity (defined as vigorous exercise at least three times per week) is associated with improved clinical outcomes in normal-weight individuals with abdominal obesity. Specifically, we compared the incidence of MACCE between normal-weight patients with type 2 diabetes who had abdominal obesity and those who did not.
Study Type
OBSERVATIONAL
Enrollment
249,247
Moderate-to-vigorous physical activity at least three times per week.
The group that did not engage in physical activity according to the guidelines
Major adverse cardiac and cerevrovascular events (MACCE)
Composite of all-cause death, myocardial infarction, ischemic stroke, heart failure
Time frame: 10 years after diagnosed T2DM
All cause death
Death from all cause
Time frame: 10 years after diagnosed T2DM
myocardial infarction
MI with hospitalization
Time frame: 10 years after diagnosed T2DM
Ischemic stroke
Ischemic stroke after diagnosed T2DM
Time frame: 10 years after diagnosed T2DM
Heart failure
HF with hospitalization
Time frame: 10 years after diagnosed T2DM
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