Integrative Chinese and Western Medicine for Knee Osteoarthritis

N/ANot Yet RecruitingNCT07072442

Chang Gung Memorial Hospital228 enrolled

Overview

This study aims to investigate if an integrated approach combining Traditional Chinese and Western medicine can better treat knee osteoarthritis. The goal is to see if this combined therapy can more effectively reduce pain severity and frequency, leading to an improved quality of life for KOA patients. Additionally, the study will explore the underlying mechanisms of pain and anti-inflammation related to KOA.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

228

Conditions

Knee Osteoarthristis

Interventions

Western MedicineDRUG

Western medicine treatment only

herbal medicine and acupuncturePROCEDURE

Western medicine combined acupuncture and herbal medicine treatemnt

herbal medicineDRUG

Western medicine combined herbal medicine

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female aged above 18 years old * Kellgren-lawrence grading scale ≥ II * Numerical rating scale (NRS) ≥ 4 Exclusion Criteria: * History of bone tumor * Pregnancy * History of bilateral knee replacement * Active infection

Outcomes

Primary Outcomes

WOMAC

Western Ontario and McMaster Universities Osteoarthritis (WOMAC) subscale

Time frame: From enrollment to 3 months after treatment completion.

NRS

Numerical rating scale (NRS) score for pain

Time frame: From enrollment to 3 months after treatment completion.

Lequesne's index

Time frame: From enrollment to 3 months after treatment completion.

Data from ClinicalTrials.gov

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