Neutrophil to Lymphocyte Ratio and Postdural Headache

Istinye University821 enrolled

Overview

This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.

Study Type

OBSERVATIONAL

Enrollment

821

Conditions

Preoperative Neutrophil-to-Lymphocyte Ratio (NLR)Postdural Puncture Headache

Interventions

PDPHOTHER

Observational analysis of preoperative inflammatory markers (e.g., NLR, PLR, SIRI) in relation to PDPH development following spinal anesthesia.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women aged 18 years or older * Underwent elective or emergency cesarean section under spinal anesthesia * Had complete preoperative complete blood count (CBC) data available * No known hematological or inflammatory disease * No intraoperative complications recorded * Medical records accessible for postoperative follow-up regarding PDPH symptoms Exclusion Criteria: * Age under 18 * Absence of preoperative complete blood count data * Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy * Platelet count \<150,000/mm³ or INR \>1.5 * Incomplete or missing medical records

Locations (1)

Istinye Üniversity

Istanbul, Merkez Mahallesi, Turkey (Türkiye)

RECRUITING

Outcomes

Primary Outcomes

Postdural Puncture Headache (PDPH) incidence

The occurrence of PDPH symptoms within 10 days following spinal anesthesia in obstetric patients, as documented in medical records.

Time frame: Within 10 days postoperatively

Central Contacts

ilke dolgun

CONTACT

+905555485632 ilkeser2004@gmail.com

Data from ClinicalTrials.gov

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