To evaluate the pharmacokinetic characteristics of HR091506 tablets in different batches in healthy subjects after single administration.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
36
In each period under fed conditions, subjects received oral administration of either HR091506 tablet(T1), HR091506 tablet(T2), or HR091506 tablet(R).
Cangzhou Central Hospital
Cangzhou, Hebei, China
Cmax: Maximum plasma concentration. Blood samples will be collected.
Time frame: From 0 hour predose up to 36 hours postdose
AUC0-t: Area under the plasma concentration-time curve from time 0 to the time of the last quantifiable concentration. Blood samples will be collected.
Time frame: From 0 hour predose up to 36 hours postdose
AUC0-∞: Area under the plasma concentration-time curve from time 0 to infinity. Blood samples will be collected.
Time frame: From 0 hour predose up to 36 hours postdose
Tmax: Observed time to reach Cmax. Blood samples will be collected.
Time frame: From 0 hour predose up to 36 hours postdose
Incidence of treatment emergent AEs (TEAEs)
Time frame: From Signing of Informed Consent Form (ICF) up to Safety Follow Up (Up to Day 24)
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