Temporal Change in Parasternal Thickening Fraction as a Predictor for Weaning

Cairo University64 enrolled

Overview

optimal time to liberate from mechanical ventilation is highly prioritized since improper extubation time lead to serious consequences

Several parameters were proposed to assess proper weaning time including diaphragmatic ultrasound and extra-diaghragmatic muscles. previous research concluded an ability of parasternal intercostal (PIC) thickening to predict weaning outcomes. researchers of current study assumed that temporal changes in PIC thickening would provide greater ability to predict weaning outcomes

Study Type

OBSERVATIONAL

Enrollment

Conditions

Mechanical Ventilation Weaning From Mechanical Ventilation Weaning Failure

Interventions

Parasternal intercostal thickeningDEVICE

Temporal change in parasternal intercostal thickening fraction at initiation and 30 minutes of spontaneous breathing trial

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Mechanically ventilated for 24 hours or more ready for weaning Exclusion Criteria: * Refusal Tracheostomized Inability to obtain ultrasound views patients with neuromuscular disease

Locations (1)

Cairo University

Cairo, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

Accuracy of change in PIC-TF in predicting successful weaning from mechanical ventilation

percentage of change in PIC TF in predicting weaning outcome (PIC TF30-PIC TF0)

Time frame: At baseline and 30 minutes after initiation of spontaneous breathing trial

Secondary Outcomes

Accuracy of change in PIC-TF to predict reintubation

percentage of change in PIC TF at start and end of spontaneous breathing trial (PIC TF30-PIC TF0)

Time frame: At baseline and 30 minutes after initiation of spontaneous breathing trial

Data from ClinicalTrials.gov

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