Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence

N/ANot Yet RecruitingNCT07084194

Minia University64 enrolled

Overview

This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical trial.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Postoperative Pain Flare up Flare Up, Symptom

Interventions

Chitosan Nanoparticles IrrigantOTHER

using Chitosan Nanoparticles irrigant as a final irrigation solution.

aloe vera nanoparticles irrigantOTHER

using Aloe Vera Nanoparticles irrigant as a final irrigation solution.

Diode Laser ActivationDEVICE

activation of nanoparticles irrigants using diode laser

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-60 (adults only) * multiple-rooted with multiple root canal. * Permanent teeth with mature apex and complete root formation. * Without root caries. * Tooth must be restorable. * Without anatomical abnormalities such as fusion. * Healthy patient category I according to ASA. * Vital tooth, with acute irreversible pulpitis and without peri-apical periodontitis. * No periapical radiolucency. * Consent Patients for who consent to participate and attend follow-up appointments. Exclusion Criteria: * single root canals or double root. * Root canal calcifications. * Root resorption or fracture. * Previously root canal treated teeth. * immunocompromised patients. * Pregnant females * Patients with systemic diseases as diabetic or hypertension patients. * Patients with facial swelling. * patients who use analgesics or antibiotics within 48-72 hours. * Allergy to any materials used (e.g., irrigants or anesthetics). * psychiatric illness * Teeth that are not indicated for endodontic treatment: bad oral hygiene, mobile teeth, or recessed teeth. * Previously endodontically treated teeth. * Teeth with sinus tract.

Outcomes

Primary Outcomes

postoperative pain intensity Postoperative pain is to be assessed using visual analog scale (VAS), A scale from (0 to 10) where "0" means no pain and "10 means a severe pain that has never faced before.

Patients will be contacted by phone at 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.

Time frame: [Time Frame: 6, 12, 24, 48, 72 hours and 7 days after the first visit to collect the postoperative pain data.]

Secondary Outcomes

Flare-Up Incidence Flare-up is assessed through asking the patient to notify the investigator if any sudden severe pain or swelling takes place.

This could require an unscheduled emergency visit or prescription of additional medication.

Time frame: [Time Frame: Within 7 days post-treatment)

Central Contacts

Rabee Ibrahaim Alhabibi

CONTACT

+201018836570 rabieibrahaim@gmail.com

Data from ClinicalTrials.gov

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