The Effect of Algae Oil Supplements on Functional Immune Response and Bioavailability of Lipids in Blood, a Pilot Study

Inclusion Criteria: * Apparently healthy men and women; * Age ≥ 50 years * Body mass index (BMI) ≥18.5 and ≤30 kg/m2; * Having veins suitable for blood sampling via a catheter (judged by study nurse/ medical doctor); * Willing to refrain from fish, fish oil, and products with added omega-3 starting from 2 weeks prior to first postprandial test day. * Willing to keep a stable dietary pattern throughout the study Exclusion Criteria: * Having a disease that may interfere with the outcomes of this study, such as a known metabolic, gastrointestinal, inflammatory or chronic disease (such as anaemia, diabetes, hepatitis, cardiovascular disease), as judged by the medical investigator; * Having a history of medical or surgical events that may significantly affect the study outcome, including: inflammatory bowel disease, hepatitis, pancreatitis, ulcers, gastrointestinal or rectal bleeding; major gastrointestinal tract surgery such as gastrectomy, gastroenterostomy, or bowel resection; known or suspected gastrointestinal disorders, colon or GI tract cancer; * Use of medication that may interfere with the study outcomes, including gastric acid inhibitors or laxatives, as judged by the medical supervisor. * Anaemia (Haemoglobin (Hb) values \<7.5 mmol/L for women and \<8.5 mmol/L for men), as assessed by finger prick blood during screening visit; * Having swallowing problems with capsules; * Allergic for fish or shellfish; * Recent blood donation (\<1 month prior to test day 1 of the study) or not willing to stop donation during and 1 month after the study; * Average alcohol intake \>21 (women) or \>28 (men) glasses of alcoholic beverages per week; * Reported weight loss or weight gain of more than 3 kg in the month prior to pre-study screening, or intention to lose weight during the study period; * Reported to follow or having planned a slimming or medically prescribed diet; * Use of drugs; * Current smokers, or stopped smoking in the last 3 months before study start; * Insufficient proficiency in Dutch to understand information brochure and questionnaires; * Participation in any clinical trial including blood sampling and/or administration of sub-stances up to 30 days before test day 1 of this study and during the study period; * Being an employee of the department Food, Health \& Consumer Research Wageningen Food \& Biobased Research or Food Quality and Design of Wageningen University.