Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder

Charite University, Berlin, Germany64 enrolled

Overview

We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.

We will investigate whether patients with Borderline personality disorder (BPD) show a negativity bias in evaluating social situations. We will also asses emotional arousal, theory of mind (ToM) abilities, and inhibitory control in patients with BPD. In addition to behavioral outcome variables, electroencephalographic (EEG) measures will be recorded. Healthy controls server as a control group.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Borderline Personality Disorder (BPD)

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: BPD diagnosis BMI between 17.5 and 30 acute major depressive episode, psychotic symptoms, substance addiction or acute suicidal behavior Exclusion Criteria: neurological, metabolic, endocrine, autoimmune and CNS diseases, any other severe somatic diseases, and pregnancy or breastfeeding during the last 12 months

Locations (1)

Dep. of Psychiatry, CBF

Berlin, Germany

Outcomes

Primary Outcomes

Number of accidental harm scenarios misclassified as intentional

Accuracy

Time frame: 20 Minutes

Data from ClinicalTrials.gov

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