The purpose of this study is to understand the characteristics of adults diagnosed with with clinically palpable stage III resectable melanoma, the associated treatment patterns for their disease, and outcomes associated with the real-world use of neoadjuvant nivolumab+relatlimab or nivolumab+ipilimumab
Study Type
OBSERVATIONAL
Enrollment
100
As prescribed by the treating clinician
As prescribed by the treating clinician
Cardinal Health
Dublin, Ohio, United States
Participant baseline demographics
Time frame: Baseline
Participant baseline clinical characteristics
Time frame: Baseline
Participant treatment history
Time frame: Baseline
Number of doses of index therapies received (neoadjuvant therapies)
Time frame: Day 1
Types of surgeries received for melanoma after the index date
Time frame: Up to 42-months
Date of last radiation received for melanoma after the index date
Time frame: Up to 42-months
Types of regimens received for melanoma post-surgery in the adjuvant setting
Time frame: Up to 42-months
Number of doses of adjuvant therapies received (post-surgery)
Time frame: Up to 42-months
Dose modifications received by participants
Time frame: Up to 42-months
Rationale for dose modifications
Time frame: Up to 42-months
Rationale for treatment discontinuation
Time frame: Up to 42-months
Overall survival (OS)
Time frame: Up to 42-months
Time to treatment discontinuation (TTD)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Up to 42-months
Duration of treatment (DOT)
Time frame: Up to 42-months
Time from neoadjuvant index treatment to adjuvant therapy
Time frame: Up to 42-months
Time from neoadjuvant index treatment to surgery
Time frame: Up to 42-months
Time from surgery to adjuvant therapy
Time frame: Up to 42-months
Pathologic complete response (PCR)
Time frame: Up to 42-months
Event-free survival (EFS)
Time frame: Up to 42-months
Distant metastasis-free survival (DMFS)
Time frame: Up to 42-months
Participant adverse events (AEs)
Time frame: Up to 42-months