Efficacy of LN18178 in Improving Muscle Strength, Aerobic Capacity and Body Composition in Healthy Young Males

Inclusion Criteria: 1. Untrained healthy male subjects aged between 36 and 50 years with a Body Mass Index (BMI) between 22 and 27 kg/m2. 2. Willingness to do exercise training program during the course of the study. 3. Subject considered generally healthy as per health history and routine clinical investigations. 4. Ability to understand the risks and benefits of the protocol. 5. Subject should provide written informed consent and agree to be available for regular follow up throughout the study duration. 6. Subjects who are sexually active must agree to use adequate non-hormonal contraception during the study 7. Subjects agree to maintain current diet and activity level. 8. Subject agrees not to start any new therapies for energy boosting supplements or protein supplements or health drinks during the course of the study. 9. Subjects willing to refrain from drinking coffee or caffeinated drinks or beverages during the study. Exclusion Criteria: 1. Subjects who are resistance trained or undergoing resistance training. 2. Subjects with blood pressure more than or equal to 140/90 mmHg, fasting plasma glucose more than 125 mg/dL and abnormal ECG. 3. Subjects underwent treatment for COVID-19 within last 3 months or tested positive during the study will be excluded. 4. Evidence or history of musculoskeletal, respiratory, haematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, neurologic diseases, malignancies. 5. Subjects diagnosed with sleep apnea or related disorders. 6. Subjects consuming medications that can interfere with muscle mass such as corticosteroids, testosterone replacement or anabolic drugs. 7. History of psychiatric disorder that may impair the ability of subjects to provide written informed consent. 8. Subjects consuming alcohol (more than 3 standard drinks per week) or smokers ( more than 3 cigarettes per day). 9. Subjects who consume recreational drugs (such as cocaine, methamphetamine, marijuana, etc.) or chewable tobacco products. 10. Subjects under medications including anti-hypertensives, antidepressants, anticholinergics, inhaled beta agonists, anti-hyperlipidemics, psychotropics etc. 11. Subjects using any centrally acting anorectic agents, drugs that inhibit the absorption of nutrients and endocannabinoid neuromodulators during the two weeks prior to enrolment into the study. 12. Subjects who underwent major surgical procedures in last 6 months. 13. Subject with HIV positive or history of any other STDs. 14. Subject has participated in a clinical study within the last 30 days prior to recruitment or concurrently participating in another study \-