This study aims to evaluate postsurgical functional changes in patients with advanced epiretinal membrane (ERM) (stages 3 and 4) by integrating a controlled macular detachment with a balanced salt solution to the conventional ERM peeling technique.
The evolution of visual acuity will be analyzed using the ETDRS letter scale. At the same time, anatomical and microvascular changes will be evaluated using optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) to evaluate their impact on visual recovery. This technique is expected to minimize persistent distortion, promote restoration of retinal perfusion, mitigate postoperative ischemia, and improve macular structural stability, potentially leading to more significant functional recovery. It is designed as a prospective longitudinal pilot study; The research will be carried out in the Retina Department of the Association to Prevent Blindness in Mexico (APEC), focusing on patients over 18 years of age with a diagnosis of advanced MRD and eligible for vitreoretinal surgery.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
36
Currently, vitrectomy with epiretinal membrane peeling is the standard procedure; however, its ability to improve visual acuity in these patients remains limited. In this context, controlled macular detachment is emerging as a surgical alternative that could optimize the anatomical and functional restoration of the retina.
Hospital Asociación Para Evitar la Ceguera en México I.A.P.
Mexico City, Mexico
RECRUITINGBCVA (Best corrected visual acuity)
Ability to discriminate fine details at a standard distance, assessed by reading letters on an ETDRS chart.
Time frame: From the first recruitment evaluation to the last one at 3 months post-surgery
Postoperative anatomical changes of the macula using optical coherence tomography: Central macular thickness (µm)
Central macular thickness measured in microns (µm)
Time frame: From enrollment to the end of follow-up at the third month.
Postoperative anatomical changes of the macula using optical coherence tomography: Inner nuclear layer thickness (µm)
Inner nuclear layer thickness measured in microns (µm)
Time frame: From enrollment to the end of follow-up at the third month.
Postoperative anatomical changes of the macula using optical coherence tomography: Ellipsoid zone disruption
Presence or absence of disruption of the Ellipsoid layer
Time frame: From enrollment to the end of follow-up at the third month.
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