This study aims to compare the effects of early and delayed time-restricted eating on metabolic syndrome parameters in obese women.
This randomized controlled trial investigates the effects of time-restricted eating with different timing windows on metabolic syndrome parameters. A total of 36 sedentary obese women aged between 20-49 years were randomly assigned to one of three groups: Early Time-Restricted Eating (eTRE; 08:00-16:00), Delayed Time-Restricted Eating (dTRE; 12:00-20:00), and a Control group (08:00-20:00). Participants' physical activity levels were assessed using a one-day physical activity log. Total energy expenditure was calculated, and a 25% energy restriction was applied to create individualized medical nutrition therapy. Anthropometric measurements, body composition, and biochemical parameters were collected before and after the 8-week intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
36
Participants followed a diet with 25% energy restriction and an 8-hour eating window from 08:00 to 16:00. Dietary compliance was monitored by dietitian through food consumption records.
Participants followed a diet with 25% energy restriction and an 8-hour eating window from 12:00 to 20:00. Dietary compliance was monitored by dietitian through food consumption records.
Participants followed a diet with 25% energy restriction and a usual eating window from 08:00 to 20:00. Dietary compliance was monitored by dietitian through food consumption records.
Baskent University
Ankara, Turkey (Türkiye)
Change in Body Weight (kg)
Body weight will be measured in kilograms using standardized procedures at baseline and at the end of the 8-week intervention.
Time frame: from enrollment to the end of treatment at 8 weeks
Change in Body Mass Index (BMI) (kg/m²)
Body Mass Index (BMI), calculated as weight (kg) divided by height squared (m²), will be recorded at baseline and at the end of the 8-week intervention.
Time frame: from enrollment to the end of treatment at 8 weeks
Change in Waist Circumference (cm)
Waist circumference will be measured in centimeters at baseline and at the end of the 8-week intervention using standardized anthropometric procedures.
Time frame: from enrollment to the end of treatment at 8 weeks
Change in Fasting Glucose (mg/dL)
Fasting blood glucose levels will be measured in mg/dL at baseline and after the 8-week intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in Fasting Insulin (μIU/mL)
Fasting serum insulin levels will be measured in μIU/mL at baseline and after the 8-week intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in HOMA-IR
Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) will be calculated using fasting glucose and insulin values at baseline and after the 8-week intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in Total Cholesterol (mg/dL)
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Serum Total Cholesterol will be measured in mg/dL at baseline and after the intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in Systolic and Diastolic Blood Pressure (mmHg)
Systolic and diastolic blood pressure will be measured using a standardized sphygmomanometer at baseline and after 8 weeks.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in LDL Cholesterol (mg/dL)
Serum LDL cholesterol will be measured in mg/dL at baseline and after the intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in HDL Cholesterol (mg/dL)
Serum HDL cholesterol will be measured in mg/dL at baseline and after the intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks
Change in Triglycerides (mg/dL)
Serum triglyceride levels will be measured in mg/dL at baseline and after the intervention.
Time frame: From enrollment to the end of the treatment at 8 weeks