Assess the uptake of rubidium-82 in parathyroid adenomas.
Parathyroid adenomas demonstrate uptake of rubidium-82 chloride and can be detected with PET imaging. The investigators aim to describe the uptake pattern of rubidium-82 chloride in parathyroid adenomas as well as compare the uptake pattern of rubidium-82 chloride to that of 18F-fluorocholine in patients with parathyroid adenoma.
Study Type
OBSERVATIONAL
Enrollment
20
PET imaging of the neck will be started immediately before infusion of 10 Megabecquerels per kilograms of rubidum-82 over 30 seconds. The acquisition will last 10 minutes. This will be followed by a non-contrast low-dose CT of the neck for localization and attenuation correction.
Montreal Heart Institute
Montreal, Quebec, Canada
Montreal Jewish General Hospital
Montreal, Quebec, Canada
Uptake pattern of rubidium-82 in parathyroid adenomas
Rudibium-82 uptake will be assessed using Maximum Standardized Uptake Value (SUVmax) and target-to-background ratios (TBR). TBR is calculated by dividing a lesion SUVmax by the mean SUV (SUVmean) or the blood pool. Maximum Standardized Uptake Value (SUVmax) and target-to-background (TBR) will be presented as median with interquartile range as well as minimum and maximum values.
Time frame: 3 months
Comparison between the uptakes of rubidium-82 and 18F-fluorocholine in patients with parathyroid adenomas
Radioactive tracer uptake will be compared between Rudibium-82 and 18F-Fluorocholine. Uptake will be assessed using Maximum Standardized Uptake Value (SUVmax) and target-to-background ratios (TBR). TBR is calculated by dividing a lesion SUVmax by the mean SUV (SUVmean) or the blood pool. Maximum Standardized Uptake Value (SUVmax) and target-to-background (TBR) will be presented as median with interquartile range as well as minimum and maximum values.
Time frame: 3 months
Pelletier-Galarneau
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