This is a prospective observational study designed to evaluate the effects of different anesthesia techniques on tissue oxygenation and postoperative recovery in patients undergoing lower abdominal surgery. A total of 180 patients will be enrolled and evenly allocated into four groups based on the anesthesia method used: general anesthesia, spinal anesthesia, epidural anesthesia, and combined general plus epidural anesthesia. Near-infrared spectroscopy (NIRS) will be utilised to monitor tissue oxygenation at the thenar and plantar regions during the perioperative period. Vital signs, VAS scores(min 0-max 10 points), Quality of Recovery-40 (QoR-40) scores(min 40-max 200 points), and additional postoperative recovery parameters- including length of stay in the post-anesthesia care unit and hospital, surgical site infection, wound revision, and mortality- will be recorded and compared across the groups. The primary hypothesis is that regional anesthesia techniques enchance tissue oxygenation and are associated with improved postoperative recovery outcomes compared to general anesthesia alone. The study was approved by the local ethics committee and will be conducted at a single tertiary-care center.
Study Type
OBSERVATIONAL
Enrollment
180
Trakya University, Faculty of Medicine
Edirne, Central, Turkey (Türkiye)
Tissue Oxygenation Levels Measured by NIRS
Continuous measurement of tissue oxygenation at thenar and plantar sites using near-infrared spectroscopy during perioperative period
Time frame: From baseline(pre-op) to end of surgery
Intraoperative Vital Signs
Systolic blood pressure recorded during anesthesia
Time frame: Intraoperative period
Intraoperative Vital Signs
Diastolic blood pressure recorded during anesthesia
Time frame: Intraoperative period
Intraoperative Vital Signs
Heart rate recorded during anesthesia
Time frame: Intraoperative period
Intraoperative Vital Signs
Oxygenation saturation recorded during anesthesia
Time frame: Intraoperative period
Visual Analog Scale(VAS) Pain Scores
VAS pain scores measured postoperatively at PACU and postoperative day 1. The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst possible pain. Higher scores indicate worse outcomes.
Time frame: Up to 24 hours after surgery
Qor-40 Questionnaire Scores
Quality of Recovery scores assessed using the Qor-40 questionnaire on postoperative day1. The total score ranges from 40 to 200, with higher scores indicating better recovery.
Time frame: postoperative day 1
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