A retrospective analysis was performed on 96 patients who underwent modified LIFT procedures to treat transsphincteric or suprasphincteric fistulas. Two distinct methods were utilized to ligate the internal sphincter side of the intersphincteric tract: one group received conventional ligation with absorbable sutures (Suturing-LIFT, n=74), while the other group was treated with absorbable clips commonly used for vascular or biliary duct occlusion (Clipped-LIFT, n=22). The primary outcome was the one-stage healing rate, which was compared between the two groups, and the safety profile of the clipped-LIFT approach was analyzed. Both univariate and multivariate analyses were conducted to identify potential prognostic factors associated with therapeutic outcomes.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
96
This group received conventional ligation with absorbable sutures
This group was treated with absorbable clips commonly used for vascular or biliary duct occlusion
Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
the one-stage healing rate
Time frame: Complete wound healing without discharge more than 6 months after the modified LIFT procedure
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