Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio

The First Affiliated Hospital of Xiamen University200 enrolled

Overview

to apply angiography-based quantitative blood flow ratio to quantify the severity of the stenosed coronary artery prior to percutaneous coronary intervention, and monitor per-procedural myocardial injury based on the troponin level.Finally, to find the relationship between quantitative blood flow ratio results and myocardial injury degree.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Coronary Arterial Disease (CAD)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * unstable angina patients Exclusion Criteria: * (1) multivessel diseases needed to be bypassed; (2) no track of high-sensitivity troponin I (hs-CTNI) level after PCI; (3) the elevated hs-CTNI level before PCI; (4) patients refusal to PCI; (5) side branch occlusion after PCI; (6) PCI failure with the main vessels occlusion; (7) eGRF (estimated glomerular filtration rate) less than 30ml/min/1.73m2; (8) no acquisition of QFR results because of the non-ideal angiographic quality.

Locations (1)

the First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China

Outcomes

Primary Outcomes

cardiovascular adverse events

Time frame: three months

Major cardiac adverse events

Time frame: three months follow-up

Data from ClinicalTrials.gov

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