We aim to study the clinical immediate and long-term efficacy of a web-delivered MBCT-L protocol targeting bachelor and master health-care students in Geneva, as well as to study the correlations of clinical, neuroimaging and biomedical effects of such an intervention. Primary objective: To evaluate the immediate and long-term effect of MBCT-L on reducing perceived stress and improving pro-social skills for health-care students, compared to a control group. Secondary objective: To evaluate the immediate and long-term effect of MBCT-L on trait mindfulness, compassion, global psychological well-being, sleep quality, anxiety, depression, satisfaction in studies and resilience, to broaden the clinical understanding of the impact of such an intervention.
This study is led jointly by Prof. C. Nemitz-Piguet, Dr F. Jermann, and Prof. S. Rudaz, who serve as co-principal investigators. This study is funded by the Swiss National Science Foundation (Grant number: 32003B\_205111 / 1)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
161
The MBCT-L (Bernard, Cullen \& Kuyken, 2017) intervention is an 8-week group intervention, comprising a pre-course orientation session, eight 2-hour sessions, and a half-day silent session. MBCT-L was delivered synchronously online. MBCT-L group were led by one MBCT-L instructor
University of Geneva
Geneva, Canton of Geneva, Switzerland
Work package 1 (WP1) - Perceived stress
Perceived stress as measured by the Perceived Stress Scale (PSS; score range: 0 -56; a higher score indicates a higher perceived stress level)
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
Work package 1 (WP1) - Prosocial skills
Prosocial skills as measured by the Prosocialness Scale for Adults (PBS; score range: 16-80; a higher score indicate a greater tendency towards prosocial behaviors).
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
Work package 2 (WP2) - Socio-affective Video Task with Resting State (SoVT-Rest)
Cortico-limbic emotion regulation network reactivity to psychological stress as measured by functional MRI (fMRI) in response to the SOVT-Rest
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
Work package 2 (WP2) - Montreal Imaging Stress Task (MIST)
Cortico-limbic emotion regulation network reactivity to psychological stress as measured by functional MRI (fMRI) in response to the MIST
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
Work package 3 (WP3) - Metabolic
Metabolic constitutive profiles
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
Work package 3 (WP3) - Lipid
Lipid signalling profiles
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP1 - Trait mindfulness
Questionnaire: Five Facets of Mindfulness Questionnaire (FFMQ); score range: 39-195. A higher score indicates a higher level of trait mindfulness
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP1 - Compassion
Sussex-Oxford Compassion Scale; compassion for the self; score range: 20-120 ; compassion for others; score range: 20-120. A higher score indicates a greater level of compassion
Time frame: T0: baseline T1: 3 months after T0 T2: 9 months after T0
WP1 - Psychological well-being
Psychological well-being scale; score range 18-108. A higher score indicates a greater psychological well-being
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP1 - Insomnia
Sleep condition indicator; score range: 0-32 A higher score corresponds to better sleep
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP1 - Anxiety and depression
Hospital Anxiety and Depression Scale; score range: 0-21 for anxiety and 0-21 for depression subscale. Higher scores correspond to higher anxiety and depression
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP1 - Satisfaction with studies
Scale of satisfaction with Studies; score range 5-35. A higher score indicates a greater degree of contentment with one's academic experience
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP1 - Resilience
Brief Resilience Scale; score range: 6-30. A higher score indicates a higher level of resilience
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP2 - Grey matter volume and functional connectivity in cortico-limbic emotion regulation networks (sMRI)
Grey matter volume and functional connectivity in cortico-limbic emotion regulation networks (sMRI)
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP2 - Resting State neuroimaging data
Resting State neuroimaging data
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP3 - Cortisol
Capillary and blood cortisol
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP3 - Oxytocine
Oxytocine
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
WP3 - Stress and inflammatory markers
Stress and inflammatory markers
Time frame: T0: baseline T1: 3 months from T0 T2: 9 months from T0
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