Effect of Collagen Membranes on Distal Periodontal Healing of Second Molars After Impacted Mandibular Third Molar Surgery.

University of Medicine and Pharmacy at Ho Chi Minh City20 enrolled

Overview

Impacted mandibular third molars can cause various complications to the adjacent second molars, such as dental caries, periodontitis, or root resorption. These complications often progress silently and asymptomatically. A typical scenario involves a mesioangularly impacted third molar exerting pressure on the distal alveolar bone of the second molar, resulting in persistent food impaction that is difficult for patients to clean. Furthermore, the surgical removal of deeply impacted or severely angulated mandibular third molars often requires bone removal in the area adjacent to the second molar. These factors may exacerbate distal periodontal defects of the second molar, especially in individuals over the age of 25. This research focuses on evaluating the effectiveness of a new-generation collagen membrane in promoting healing after the extraction of impacted mandibular third molars in patients at risk of distal periodontal tissue damage to the second molars

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Periodontal Defect

Interventions

Eligibility

Sex: ALLMin age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged 25 years or older. * Patients with mesioangular or horizontally impacted mandibular third molars. The highest point of mandibular third molars are lower than the occlusal surface of adjacent second molars (classified B, C according to Pell - Gregory's category). * Patients with symmetrical lower third molars on both sides with same classification according to Pell - Gregory's category. The difference of third molars inclination on both side is not more than 15°. * Patients with lower second molars on both sides have no cavities or fillings that affect the determination of the cemento-enamel junction. * Patients are explained, counseled clearly and sign their consent to participate in the study. Exclusion Criteria: * Patients with coagulation or immune disorders. * Patients allergic to local anesthetics (Lidocaine 2% with Adrenaline 1:100,000) or any drugs used in the study. * Patients allergic to products or food derived from pigs. * Pregnant or breastfeeding patients. * Patients who smoke. * Patients with systemic conditions that contraindicate surgical procedures. * Patients with clinical or radiographic signs suggestive of tumors (benign or malignant) associated with or in proximity to the mandibular third molar. * Patients with missing mandibular second molars.

Outcomes

Primary Outcomes

Distal periodontal tissue status

distal periodontal tissue status was assessed using variables of pocket depth

Time frame: preoperative (T0), 3rd moth after surgery (T3) and 6th month after surgery (T6)

Secondary Outcomes

Distal bone level

The variable was determined by measuring the distance from the CEJ of mandibular second molar to the highest point of the alveolar crest, performed with the periapical radiograph using the parallel technique, standardized with a film holder and a stent with a 5 mm steel segment

Time frame: at the time of the end of surgery (T0'), 3rd month after surgery (T3), and 6th month after surgery (T6).