Posterior Circulation Clot Burden Score (Pc-CBS) Predicts Clinical Outcome After Acute Ischemic Stroke Related to Posterior Circulation Occlusions : An Externally Validated Radiological Score

Centre Hospitalier Universitaire Vaudois1,828 enrolled

Overview

Posterior circulation strokes (PCS) represent \~30% of all ischemic strokes, but existing prognostic tools are limited, especially for non-basilar artery occlusions. Accurate early outcome prediction may aid treatment decisions and clinical trial design. We developed and externally validated the Posterior Circulation Clot Burden Score (PC-CBS), a radiological tool to predict 3-month functional outcome in acute ischemic stroke due to posterior circulation occlusion.

Study Type

OBSERVATIONAL

Enrollment

1,828

Conditions

Acute Ischemic Stroke Posterior Circulation Brain Infarction Arterial Occlusion Disease

Interventions

Assessment of cervico-cerebral arterial occlusion pattern

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age \>18 years old * admitted within 24h from last known well * symptomatic arterial occlusion. The following arterial occlusions were eligible for inclusion: the extracranial vertebral artery between the V0 and V3 segments; the intracranial portion of the vertebral artery; the basilar artery either in its proximal, mid and/or distal segment, the P1 and/or the P2 segments of the posterior cerebral artery. Exclusion Criteria: * simultaneous clinical and/or radiological strokes in the posterior and anterior circulation

Posterior Circulation Clot Burden Score (Pc-CBS) Predicts Clinical Outcome After Acute Ischemic Stroke Related to Posterior Circulation Occlusions : An Externally Validated Radiological Score

Overview

Conditions

Interventions

Eligibility

Outcomes

Primary Outcomes