a Comparison of the Outcomes Following Intra-articular Dextrose 5% Injection Versus Arthrocentesis in Patients With Anterior Disc Displacement With Reduction of the Tomporomandibular Joint

N/ANot Yet RecruitingNCT07129681

Cairo University42 enrolled

Overview

The Aim of this study is to evaluate the efficacy of intra-articular Dextrose injection with concentration 5% in superior joint space of TMJ in comparison to arthrocentesis in patients with anterior disc displacement with reduction of TMJ who did not respond favorably to conservative treatment and to compare and infer which among the two procedures is more satisfactory, whether dextrose 5% injection or Arthrocentesis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

TMJ Disc Disorder

Interventions

Arthrocentesis/SalineOTHER

Arthrocentesis , a highly successful, simple and minimally invasive procedure is a safe and simple method for treatment of anterior disc displacement with reduction of TMJ both in short term and long term follow up period, where it is a procedure of removing damaged tissues \&inflammatory mediators.it can be the treatment modality for the for control group

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Inclusion Criteria -Patients diagnosed with anterior disc displacement with reduction of TMJ with pain,limited mouth opening and painful clicking who underwent conservative therapy with physiotherapy but failed to receive any relief after 3 months of conservative therapy. * Age ranges from 18 to 50 years. * Patients with adequate follow up duration for outcome assessment. Exclusion Criteria: * Patients having pain or reduced mouth opening due to fracture of the condyle. * patients having any degenerative changes in the TMJ. * patients having other systemic diseases such as polyarthritis. * patients having any neurological disorders. * Pregnant and lactating women.

Outcomes

Primary Outcomes

Change in Pain Severity Measured by Numerical Rating Scale (NRS)

Primary Outcome Measure: 1\. Change in Pain Severity Measured by Numerical Rating Scale (NRS) Pain severity will be assessed using the Numerical Rating Scale (NRS) (0-10), where 0 = no pain and 10 = severe pain. Participants will report their pain levels at each time point. The mean change in NRS scores from baseline will be calculated and analyzed . Data Aggregation: Mean change in NRS score

Time frame: Measured at baseline, 3 days and 3 months after injection

Secondary Outcomes

Change in Maximal Interincisal Opening (MIO) Measured in Millimeters

Maximal interincisal opening (MIO) will be measured using a sterilllized metal scale or a digital caliper, with values recorded in millimeters (mm). The mean change in MIO from baseline will be reported . Data Aggregation: Mean change in MIO (mm) with standard deviation (SD).