This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
10
4 week intervention consisting of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in combination with 3 days per week of High-Intensity Interval Training (HIIT) exercise
Texas Woman's University Houston Center
Houston, Texas, United States
To determine the feasibility of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT in adults with HTN and overweight/obesity.
Adherence to the lifestyle intervention will be determined by ≥ 75% supervised exercise training visits completed and ≥ 75% dietary compliance.
Time frame: From baseline to end of treatment at 4 weeks
To evaluate the efficacy of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT to lower blood pressure in adults with HTN and overweight/obesity.
Clinic-based blood pressure will be measured in triplicate at each testing visit using a Welch Allyn Automated Blood Pressure Unit and 24-hour blood pressure will also be measured using SunTech Oscar 2 Ambulatory Blood Pressure Monitors
Time frame: Baseline and end of intervention at 4 weeks
To evaluate the efficacy of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT to improve nocturnal blood pressure in adults with HTN and overweight/obesity.
Nocturnal blood pressure will be measured using SunTech Oscar 2 Ambulatory Blood Pressure Monitors
Time frame: At baseline and at the end of the 4 week intervention
To evaluate the efficacy of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT to improve cardiorespiratory fitness in adults with HTN and overweight/obesity.
Cardiorespiratory fitness will be assessed via maximal oxygen uptake (VO2max) on a cycle ergometer
Time frame: Baseline and end of intervention at 4 weeks
To evaluate the efficacy of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT to improve cardiometabolic blood biomarkers in adults with HTN and overweight/obesity.
Fasting blood will be drawn, processed, and analyzed for glucose, insulin, lipids, and inflammatory markers.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: At baseline and end of the intervention at 4 weeks
To evaluate the efficacy of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT to lower visceral fat in adults with HTN and overweight/obesity.
Visceral fat will be measured via dual-energy x-ray absorptiometry (DEXA)
Time frame: Baseline and end of intervention at 4 weeks
To evaluate the efficacy of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT to improve quality of life in adults with HTN and overweight/obesity.
Health-related quality of life will be measured with the 36-item Short-Form Health Survey (SF-36)
Time frame: Baseline and at the end of the intervention at 4 weeks