Analysis of peripheral immune cells before, during, and after brachytherapy treatment. Corresponding analysis of tissue samples collected during brachytherapy treatment.
Study Type
OBSERVATIONAL
Enrollment
200
Klinik für Strahlentherapie
Augsburg, Bavaria, Germany
NOT_YET_RECRUITINGStrahlenklinik Erlangen
Erlangen, Bavaria, Germany
RECRUITINGKlinik und Poliklinik für Strahlentherapie und Radioonkologie
Munich, Bavaria, Germany
NOT_YET_RECRUITINGLongitudinal changes of peripheral immune cells and cell-free DNA and tumor-associated tissue in patients with prostate cancer treated with brachytherapy
Longitudinal changes of peripheral immune cells and cell-free DNA and tumor-associated tissue in patients with prostate cancer treated with brachytherapy in the primary as well as in the recurrent setting.
Time frame: Blood withdrawal pre-brachytherapy treatment, during surgery, one day after brachytherapy and at the first follow-up visit 4-12 weeks later. Tissue samples at every brachytherapy procedure.
Treatment-related toxicity
Acute toxicity related to brachytherapy
Time frame: Up to 6 months
recurrence-free survival
recurrence-free survival
Time frame: Up to 6 months
Overall survival
Overall survival
Time frame: Up to 6 months
Anna-Jasmina Donaubauer, Dr. rer. nat.
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