Associations Between Time to Reduction and Complications in Patients With Dislocated Total Hip Arthroplasty

N/ANot Yet RecruitingNCT07132723

Nordsjaellands Hospital3,700 enrolled

Overview

The aim of the study is to investigate the impact of time to closed reduction on both patient related and organizational factors. These include, length of stay, hospitalization, admission to intensive care unit, rehospitalizations, delirium, all-cause mortality, infection requiring hospital contact, and cardiovascular complications. It is also intended to investigate whether different anaesthetic strategies and airway management are associated with different complication rates. It is hypothesized that longer waiting time until reduction increase the postoperative length of stay, readmissions, and risk of complications.

Study Type

OBSERVATIONAL

Enrollment

3,700

Conditions

Closed Reduction Arthroplasty, Replacement, Hip Length of Stay

Interventions

Time in minutes from admission to closed reduction

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients will be considered eligible for inclusion if they meet all of the following criteria: * Aged 18 years or older * Presented to the emergency department with a dislocated total hip arthroplasty. * Undergo closed reduction of the dislocated total hip arthroplasty in the operating theatre, with the involvement of the Department of Anesthesiology. Exclusion Criteria: * Were primarily booked for open surgical reduction. * Did not have a complete case log (i.e. time of admission; referral to the operation theatre; anesthesia induction; discharge, etc.) and we were unable to recreate the log using simple code rules.

Outcomes

Primary Outcomes

Post procedure length of stay

Post procedure length of stay from closed reduction until discharge from the hospital (hours)

Time frame: 30 days after the closed reduction

Secondary Outcomes

All-cause mortality

90 days all-cause mortality (Y/N)

Time frame: 90 days after closed reduction

Admissions to Intensive care unit

Admissions to the intensive care unit within 30 days after the closed reduction.

Time frame: 30 days after the closed reduction

Readmission

Readmission within 30 days after discharge

Time frame: 30 days after discharge

Delirium during admission

Defined as diagnose of delirium (F05.x, obtained from the diagnosis codes from the given admission) or the non-planned administration of haloperidol, olanzapine, risperidone, or quetiapine (as a surrogate for new onset delirium)

Time frame: From admission to discharge up to 30 days after closed reduction

Acute kidney failure

Defined as serum creatinine increase of more than 25 μmol/L within a period of less than 48 hours. (As a surrogate for acute kidney failure)

Time frame: Post procedure until 30 days after discharge

Infection requiring hospital contact

Defined as diagnosed infection (postoperative infection (T81.4), pneumonia (J13.x-J18.x), Cystitis (N30.x, N39.0), sepsis (R65.x A40.x, A41.x), C. difficile (A04.7) obtained from the diagnose codes from the given admission) or administration of antibiotic treatment (as a surrogate for in-hospital infection

Time frame: Post procedure until 30 days after discharge

Cardiovascular complications

Defined as diagnosed arrythmia (I47.x, I48.x, I49.x), myocardial infarction (I21.x, I22.x), cerebral ischemia (I61.x, I63.x, I64.x), hemorrhage(T81), pulmonary embolism(I26.x) or deep venous thrombosis(I80.2) (obtained from the diagnosis codes from the given admission)

Time frame: From admission to 30 days after discharge.