This is a single center, randomised and controlled clinical triaI whose aim is to predict and treat in advance, intraoperative hypotension episodes. In particular, the aim of the study is to compare the clinical impact of two different hemodynamic strategies based on the use of different monitoring platforms: the Edwards EV1000 equipped with FloTrac sensor and HemoSphere platform equipped with Acumen Hypotension Prediction Index software and Acumen IQ pressure sensor.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
534
Hemodynamic management protocol based on information detected by Edwards HemoSphere monitor equipped with the Acumen Hypotension Prediction Index software (HPI)
Current clinical hemodynamic care
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy
MINS and AKI incidence
Clinical impact of any reduction in IOH occurrence or severity
Time frame: within 3 and 7 days after surgery
Mortality
Time frame: 30 days
Cardiac damage
Measure of serum high-specific Troponin I
Time frame: from day 1 to 3
kidney damage
measure of creatine
Time frame: day 1, day 2 and day 7
hypotensive events
severity and time-weighted average
Time frame: 2 years
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