A multicenter, open-label, non-interventional study evaluates the safety and tolerability of oral Dimolegin® (60 mg once daily) for thromboprophylaxis in hospitalized adults (≥18 years) with moderate COVID-19 in real clinical pratice. The primary objective is to assess safety and tolerability of Dimolegin® in preventing thrombotic complications.
Study Type
OBSERVATIONAL
Enrollment
184
Dimolegin® is administered orally once daily,The recommended dose is 60 mg (six 10 mg tablets) once daily.
Regional Clinical Hospital No. 3
Chelyabinsk, Russia
Republican Clinical Hospital named after Professor A.F. Agafonov
Kazan', Russia
Infectious Diseases Clinical Hospital No. 1
Moscow, Russia
Infectious Diseases Hospital No. 2
Sochi, Russia
Frequency of major bleeding events
Time frame: through discharge from the hospital, up to 30 days
Frequency of major bleeding events
Time frame: up to 60±3 days
Frequency of moderate bleeding events
Time frame: up to 60±3 days
Frequency of minor bleeding events
Time frame: up to 60±3 days
Frequency of anemia
Time frame: up to 60±3 days
Frequency of AR of special interest regardless of severity
Time frame: up to 60±3 days
Proportion of patients with ARs and SARs
Time frame: up to 60±3 days
Change from baseline in INR, APTT, prothrombin time, and D-dimer levels
Time frame: through discharge from the hospital, up to 30 days
Frequency of gastrointestinal symptoms
Time frame: through discharge from the hospital, up to 30 days
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Tomsk Regional Hospital
Tomsk, Russia
Regional Infectious Diseases Clinical Hospital
Yaroslavl, Russia