This interventional study will investigate the effects of stroboscopic visual conditions on gait patterns and lower limb muscle activation in adults with chronic ankle instability (CAI). CAI often results in impaired sensorimotor control, leading to altered gait strategies such as slower walking speed, shorter step length, and increased visual reliance. Stroboscopic glasses intermittently restrict visual input, potentially reducing visual dependence and enhancing proprioceptive feedback. Participants will complete walking trials under three randomized visual conditions: high-frequency stroboscopic, low-frequency stroboscopic, and no-glasses control. Gait parameters will be measured using the GAITRite system, and surface electromyography (sEMG) will record activation of the tibialis anterior, peroneus longus, and gastrocnemius muscles. Findings may provide insight into sensorimotor adaptation mechanisms and inform rehabilitation strategies to improve functional stability in individuals with CAI.
Chronic ankle instability (CAI) is a frequent outcome after ankle sprains, characterized by recurrent giving-way episodes, pain, and functional limitations. Approximately 40% of individuals with ankle sprains develop CAI, which is associated with deficits in proprioception, neuromuscular coordination, and postural stability. Increased visual reliance is a common compensatory strategy, but this can impair balance and gait when visual input is limited, raising the risk of re-injury. Stroboscopic glasses alternate between transparent and opaque states, intermittently restricting visual information. This challenges the sensorimotor system, potentially reducing visual dependence and enhancing proprioceptive engagement. Prior research has shown benefits for static and dynamic balance, but little is known about effects on walking in CAI populations. This randomized crossover study will assess the impact of high-frequency and low-frequency stroboscopic visual conditions compared with normal vision on gait and lower limb muscle activation in CAI. Adults aged 18-45 years with CAIT scores \< 24 and a history of ankle instability within 6 months will be recruited. Exclusion criteria include recent lower limb surgery/fracture, systemic conditions affecting balance, or inability to follow instructions. Participants will perform walking trials on a 5-meter GAITRite walkway under three randomized visual conditions: 1. High-frequency stroboscopic (rapid alternation) 2. Low-frequency stroboscopic (slower alternation) 3. No-glasses control (normal vision) Gait parameters (step length, step time, gait velocity, swing/stance phases) will be measured, and sEMG (Noraxon) will assess activation of the tibialis anterior, peroneus longus, and gastrocnemius, normalized to MVIC. Subjective measures include CAIT, FAAM, IdFAI, and VAS pain scores. It is hypothesized that stroboscopic conditions will produce measurable changes in gait and muscle activity compared with control, reflecting adaptive sensorimotor strategies that can inform rehabilitation programs to improve stability, mobility, and reduce re-injury risk.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
25
Participants will perform walking trials under three visual conditions: high-frequency stroboscopic glasses, low-frequency stroboscopic glasses, and no-glasses control. Each participant will complete three 5-meter walking trials per condition, with the order of conditions randomized. Gait parameters will be recorded using the GAITRite walkway system, and muscle activity will be measured using surface electromyography.
Sahmyook University
Seoul, South Korea
Change in Gait Velocity (cm/s) Under Different Stroboscopic Visual Conditions
Gait velocity will be measured using the GAITRite system under three visual conditions: high-frequency stroboscopic, low-frequency stroboscopic, and no stroboscopic. Each participant will perform three walking trials per condition over a 5-meter walkway. The average gait velocity (cm/s) will be calculated for each condition.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Step Length (cm) Under Different Stroboscopic Visual Conditions
Step length will be measured using the GAITRite system under three visual conditions. The average value (cm) will be calculated for each condition.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Step Width (cm) Under Different Stroboscopic Visual Conditions
Step width will be measured using the GAITRite system under three visual conditions.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Swing Phase (%) Under Different Stroboscopic Visual Conditions
Swing phase duration as a percentage of the gait cycle will be measured using the GAITRite system under three visual conditions.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Single Limb Support (%) Under Different Stroboscopic Visual Conditions
Single limb support duration as a percentage of the gait cycle will be measured.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Double Limb Support (%) Under Different Stroboscopic Visual Conditions
Double limb support duration as a percentage of the gait cycle will be measured.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Tibialis Anterior Muscle Activation (%MVIC) Under Different Stroboscopic Visual Conditions
Surface electromyography (sEMG) will measure tibialis anterior muscle activation during walking. Data will be normalized to maximum voluntary isometric contraction (%MVIC).
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Peroneus Longus Muscle Activation (%MVIC) Under Different Stroboscopic Visual Conditions
sEMG will measure peroneus longus muscle activation during walking, normalized to %MVIC.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Change in Gastrocnemius Muscle Activation (%MVIC) Under Different Stroboscopic Visual Conditions
sEMG will measure gastrocnemius muscle activation during walking, normalized to %MVIC.
Time frame: Day 1 (single experimental session; immediately after each walking condition)
Correlation Between Foot and Ankle Ability Measure - ADL Subscale (FAAM-ADL) Score and Gait Velocity (cm/s)
Pearson's correlation will be computed between FAAM-ADL score (0-100; higher scores indicate better function) and gait velocity.
Time frame: Day 1 (questionnaire administered before walking tasks)
Correlation Between Foot and Ankle Ability Measure - Sports Subscale (FAAM-Sports) Score and Gait Velocity (cm/s)
Pearson's correlation will be computed between FAAM-Sports score (0-100; higher scores indicate better function) and gait velocity.
Time frame: Day 1 (questionnaire administered before walking tasks)
Correlation Between Identification of Functional Ankle Instability (IdFAI) Score and Gait Velocity (cm/s)
Pearson's correlation will be computed between IdFAI score (0-30; higher scores indicate greater instability) and gait velocity.
Time frame: Day 1 (questionnaire administered before walking tasks)
Correlation Between Visual Analogue Scale (VAS) Pain Score and Gait Velocity (cm/s)
Pearson's correlation will be computed between VAS pain score (0-10; higher scores indicate more severe pain) and gait velocity.
Time frame: Day 1 (questionnaire administered before walking tasks)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.