The goal of this clinical trial is to learn if Neem works to treat Oral Lichen Planus in adults. It will also learn about the safety of Neem in oral lesions. The main questions it aims to answer are: To compare the efficacy of 1.5% Neem Gel (Azadirachta Indica) versus 0.1% Triamcinolone Acetonide in treatment of Oral Lichen Planus (OLP) as a topical treatment modality for patients with OLP, Researchers will compare Neem to a corticosteroid (a standard treatment for Oral Lichen Planus) to see if Neem works to treat Oral Lichen Planus. Participants: In experimental group were given Neem Gel in Orabase formulations and control group with topical Triamcinolone acetonide oral paste to be used twice every day for 3 months Visit the clinic once every month for checkups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
1.5% Neem Gel in orabase formulation, twice daily application for 3 months
0.1% oral paste to be applied twice daily for 3 months
Department of Oral Medicine and radiology, Goa Dental College and Hospital, Bambolim Goa India
Goa, Bambolim, India
Visual Analogue Scale
Burning sensation will be evaluated with Visual Analogue scale
Time frame: From enrollment to the end of 3 months
Thongprasom's Score
clinical severity of lesion
Time frame: From enrollment to the end of the 3 months
OLP Disease Severity Score
Site, size and severity of lesion
Time frame: From enrollment to the end of 3 months
Hospital Anxiety and Depression Scale
Anxiety and depression evaluation among patients
Time frame: From Enrollment to the end of 3 months
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