The primary objective of the study is to evaluate the pharmacokinetics (PK) of teprotumumab after a single intravenous (IV) infusion of teprotumumab in healthy Chinese participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
20
Administered via IV infusion.
Administered via IV infusion.
Huashan Hospital, Fudan University
Shanghai, Shanghai Municipality, China
Maximum Observed Serum Concentration (Cmax) of Teprotumumab
Time frame: Up to Day 85
Area Under the Serum Concentration-time Curve From Time Zero to the Last Quantifiable Concentration (AUClast) of Teprotumumab
Time frame: Up to Day 85
Area Under the Serum Concentration-time Curve From Time Zero to Infinity (AUCinf) of Teprotumumab
Time frame: Up to Day 85
Number of Participants With Treatment-emergent Adverse Events
Time frame: Up to Day 85
Number of Participants With Serious Adverse Events
Time frame: Up to Day 85
Number of Participants With Anti-teprotumumab Antibodies
Time frame: Up to Day 85
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