The purpose of this study is to determine the safety, tolerability and preliminary efficacy of NEUK203-215 , a healthy donor (HD) allogeneic CD19/BCMA-targeted CAR-NK cell product, in participants with severe, refractory autoimmune diseases.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
8
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Shanghai Changzheng Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGAdverse events
Time frame: Up to 12 months post NEUK203-215 infusion
Existence/non existence of dose limiting toxicity (DLT)
Time frame: Up to 12 months post NEUK203-215 infusion
serious adverse events (SAEs)
Time frame: Up to 12 months post NEUK203-215 infusion
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