2311 TURGOR Study -Surgical Efficiency and Postoperative Corneal Clarity With Near Physiologic vs High IOP Settings

Inclusion Criteria: * Patients with cataract and otherwise healthy eyes, not exhibiting any significant ocular morbidity that would be expected to influence outcome measures. * Patients undergoing phacoemulsification surgery (OU) with or without femtosecond laser assistance (OU) with the Alcon Centurion system using Active Sentry handpieces (both eyes must undergo same treatment) . The cataract surgery and the use of the medical device(s) are planned by the principal investigator and are a part of regular care and are received regardless of being a part the study. * Patients expected to undergo sequential cataract surgery in both eyes within 6 weeks of each other. * Patients with the same LOCS III scale of nuclear portion of cataract in both eyes * Patients whose eyes will both be operated by the same surgeon using a similar Centurion machine with similar wound architecture and size, viscoelastic, technique, and postoperative medications. * Axial eye length cannot vary between eyes by more than 0.4 mm in an individual patient. * At least 30% of patients with PanOptix, 30% Vivity and 30% monofocal IOLs (no mix and match) Exclusion Criteria: * Patients with visually significant co-morbidities (corneal, retina, optic nerve disease) that could affect the surgical outcome measures. * Clinically significant ocular trauma. * Patients with unusually dense cataract (4+ nuclear sclerosis), zonular instability, or pseudoexfoliation syndrome * Patients requiring mechanical pupil expanding devices (iris hooks, Malyugin rings, etc.) * Patients with surgical complications either during or after surgery (capsule tears, iris trauma, decentered IOL) * Ocular surgery (e.g., intraocular, oculoplastic, corneal or refractive surgical procedure performed within the last 3 months or at any time that in the investigator's clinical judgment if it would interfere with the outcome measures of this study. * Reported pre-existing anxiety or pain disorder or history of psychiatric illness, chronic pain/narcotics, benzodiazepine usage. * Epitheliopathy/ Epithelial complications intraoperatively that may in the opinion of the investigator affect corneal densitometry or edema postoperatively. * Clinically significant IOL decentration * Vulnerable populations which includes, but is not limited to potential subjects who are children, prisoners, pregnant women, mentally disabled persons, and economically and educationally disadvantaged persons.