Placental Risk Assessment to CusTomize Individualized Pregnancy Care and Evaluation

Oregon Health and Science University640 enrolled

Overview

This is a prospective observational study with the goal of developing and assessing a predictive model of placental insufficiency.

Pregnant study participants will be recruited and monitored throughout pregnancy with ultrasound and blood draws, and delivery and neonatal data up to 28 days following birth. This data will be used to develop a model to predict placental insufficiency.

Study Type

OBSERVATIONAL

Enrollment

640

Conditions

Stillbirth Placental Insufficiency

Interventions

Data Collection Throughout Pregnancy and DeliveryOTHER

Participants will receive monitoring by ultrasound and blood tests at three time points during pregnancy, and delivery and neonatal data will be collected.

Eligibility

Sex: FEMALEMin age: 15 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant * Age 15 or older * No known major fetal anatomic or genetic abnormalities * Singleton gestation * Planning to deliver at Oregon Health \& Science University * Prior to 22 weeks' gestation Exclusion Criteria: * Decisional impairment * Multiple gestation * Known fetal growth restriction or major congenital anomaly * Inability to consent * Inability to attend study visits

Locations (1)

Oregon Health & Science University

Portland, Oregon, United States

RECRUITING

Outcomes

Primary Outcomes

Number of participants with placental insufficiency composite

The composite is made of the following: stillbirth and neonatal death, severe forms of hypertensive disease, placental abruption, birthweight below the 3rd percentile, umbilical cord arterial pH\<7, and/or placental primary indication for delivery (FGR, oligohydramnios, abnormal fetal testing)

Time frame: At time of delivery to 28 days following delivery

Central Contacts

Women's Health Research Unit Department of Ob/Gyn

CONTACT

503-494-3666 whru@ohsu.edu

Data from ClinicalTrials.gov

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