The goal of this clinical trial is to examine the effect of a respiratory muscle strengthening program on the cognitive and physical functioning of patients with neurocognitive disorders (Mild Cognitive Impairment) or those predisposed to them. The main questions that aims to answer are: 1. Is Inpsiratory Muscle Training (IMT) feasible in people with mild cognitive impairement? 2. Could Inspiratory Muscle Training (IMT) improve congitive function in people with mild cognitive impairement? 3. Could Inspiratory Musclre training improve physical function in this population? Participants will be: 1. \< 60 age or \> 90 age 2. MMSE (Mini Mental State Examination) score ≤ 28 and ≥ 18 and follow a high intensity IMT program along with a physical - cognitive program. or just the physical - cognitive program.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
76
Participants will follow an IMT program through a threshold IMT device which consists of 5 set/6 breaths at 50-60% MIP for 3 months along with their usual physical and cogntive training
Physical and cognitive training
University of West Attica
Aigáleo, Attica, Greece
RECRUITINGMini Mental State Examination
Time frame: T0 at the beginning, T1 at 3 months (end of intervention), T2 at 6 months (follow-up)
Frontal Assessment Battery
Time frame: T0 at the beginning, T1 at 3 months (end of intervention), T2 at 6 months (follow-up)
Addenbrooke's Cognitive Examination
Time frame: T0 at the beginning, T1 at 3 months (end of intervention), T2 at 6 months (follow-up)
Time up and Go (TUG)
Time frame: T0 at the beginning, T1 at 3 months (end of intervention), T2 at 6 months (follow-up)
Sit-to-Stand test
Time frame: T0 at the beginning, T1 at 3 months (end of intervention), T2 at 6 months (follow-up)
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