This is a research study. The over-the-counter (OTC) drug for atopic dermatitis being tested is not approved as a treatment for the participants' atopic dermatitis condition. In participating in this study, the investigators will analyze the participants' skin microbiome, measure skin hydration and barrier function, and assess clinical improvements to help us understand the potential impact of the investigational OTC drug on atopic dermatitis and skin microbiome balance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
36
OTC Cosmetic Cream Formulation
Sequential Skin
New York, New York, United States
RECRUITINGSkin Microbiome Composition and Diversity using qPCR analysis
Time frame: 4 weeks
Trans-Epidermal Water Loss Measurement via Vapometer
Time frame: 4 weeks
Moisturizing effect by measurement of cutaneous hydration via MoistureMeterSC
Time frame: 4 weeks
Skin barrier lipid composition and integrity via lipidomic profiling analysis
Time frame: 4 weeks
Before and After Treated Arm Itching Assessment
In vivo clinical grading by a technician using a 11 point scale (0 = uncomfortable, irritated, and 10 = comfortable, soothed)
Time frame: 4 weeks
Before and After Treated Arm Redness Assessment
In vivo clinical grading by a technician using a 5 point scale (0 = absence of redness, and 4 = severe intensity)
Time frame: 4 weeks
Before and After Treated Arm Skin Dryness Assessment
In vivo clinical grading by a technician using a 11 point scale (0 = dry, cracked skin, and 10 = well-hydrated skin)
Time frame: 4 weeks
Monitoring of Atopic Dermatitis/Eczema Severity
Via the Patient Oriented Eczema Measure (POEM) tool
Time frame: 4 weeks
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