The feasibility and safety of minimally invasive surgery in cases after neoadjuvant therapy were unclear. It is worth exploring the safety of robotic resection for pancreatic cancer following neoadjuvant therapy. The investigators investigated the comparative outcomes of robotic and open surgery in the management of pancreatic cancer after NAT, exploring the feasibility and safety of robotic procedures in complex cases of pancreatic cancer, and providing evidence-based guidance for clinical practice.
Currently, most studies focus on upfront resectable pancreatic cancer, benign or low-grade malignant tumors, demonstrating that robotic surgery can shorten postoperative hospital stays, reduce intraoperative blood loss, and achieve oncological outcomes comparable to open surgery. The feasibility and safety of minimally invasive surgery in cases after NAT were unclear. Both the Miami international evidence-based consensus and the Brescia international validated European guidelines indicate that current data are insufficient to recommend minimally invasive approaches for pancreatic cancer resection following NAT, highlighting the need for additional research. Therefore, it is worth exploring the safety of robotic resection for pancreatic cancer following NAT. The investigators investigated the comparative outcomes of robotic and open surgery in the management of pancreatic cancer after NAT, exploring the feasibility and safety of robotic procedures in complex cases of pancreatic cancer, and providing evidence-based guidance for clinical practice.
Study Type
OBSERVATIONAL
Enrollment
56
Department of General Surgery, Peking Union Medical College Hospital (PUMCH)
Beijing, Beijing Municipality, China
Overall complication
The complication occurred within 90 days after the surgery
Time frame: Until the 90 days after surgery
Clinically relevant postoperative pancreatic fistula
Grade B or C pancreatic fistula within 90 days after surgery
Time frame: Until the 90 days after surgery
Postoperative pancreatectomy hemorrhage
Hemorrhage occurred within 90 days after surgery
Time frame: Until the 90 days after surgery
Disease-free survival
The length of time from the completion of surgery until the recurrence of cancer, the occurrence of metastasis, death from any cause, or to the last follow-up.
Time frame: Up to 2 years after the surgery
Overall survival
The length of time from the date of surgery to death from any cause or to the last follow-up.
Time frame: Up to 2 years after surgery
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