Orchiopexy is a common surgical procedure for the treatment of cryptorchidism in the pediatric population, with a high incidence of postoperative nausea and vomiting (PONV). Recent evidence suggests that systemic inflammation may contribute to PONV pathogenesis, and preoperative inflammatory biomarkers such as NLR, PLR, SII, MLR, and SIRI could serve as predictive indicators. This prospective observational study aims to evaluate the relationship between these biomarkers and PONV incidence in children undergoing orchiopexy.
Study Type
OBSERVATIONAL
Enrollment
170
Blood samples will be collected preoperatively to measure inflammatory biomarkers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index, monocyte-to-lymphocyte ratio (MLR), and systemic inflammation response index. These values will be analysed in relation to the incidence of postoperative nausea and vomiting within the first 6 hours after pediatric orchiopexy. No experimental drug or device will be administered as part of the study; all procedures will be conducted within the scope of standard perioperative care.
Ankara Etlik City Hospital
Altındağ, Ankara, Turkey (Türkiye)
RECRUITINGIncidence of Postoperative Nausea and Vomiting (PONV)
PONV will be assessed using a standardized nausea-vomiting scoring system by an anesthesiologist blinded to biomarker results.
Time frame: Within 6 hours postoperatively
Need for Antiemetic Treatment
The number of patients who receive at least one dose of rescue antiemetic medication will be recorded within the first 6 hours after surgery.
Time frame: Within 6 hours postoperatively
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