Surgery Benefits Takayasu Arteritis With Stenosis in the Descending Aorta

Peking Union Medical College Hospital78 enrolled

Overview

The long-term prognosis and optimal management for Takayasu arteritis(TA) patients with severe stenosis of the descending thoracic and abdominal aorta remain undefined. We want to compare the clinical outcomes of surgical intervention and medical management.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Takayasu Arteritis

Interventions

open surgery or interventional treatmentPROCEDURE

open surgery or interventional treatment

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. fulfilling the 1990 American College of Rheumatology criteria for the diagnosis of TA; 2. having at least one site with severe narrowing in the descending thoracic and abdominal aorta; 3. having symptoms caused by TA-related stenosis, such as uncontrolled hypertension, heart failure, renal ischemia, dizziness, visual disturbances, and claudication Exclusion Criteria: Patients with arterial stenosis due to other reasons (such as typical atherosclerosis, congenital coarctation of the aorta, and anatomical abnormality) were excluded

Outcomes

Primary Outcomes

all-cause mortality rate

Time frame: Patients underwent follow-up from discharge until study termination (3 years to 11 years) or death, whichever came first

all-cause mortality rate

Time frame: Patients underwent follow-up from discharge (3 years to 11 years) until study termination or death, whichever came first

Data from ClinicalTrials.gov

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