A multicenter, open-label, randomized, controlled study. It is proposed to evaluate the treatment plan of receiving 930mg polyene phosphatidylcholine injection one day before the operation, twice a day, and 930mg polyene phosphatidylcholine injection twice a day,combined with 100mg of magnesium isoglycyrrhizinate injection once a day,from the 1st to the 5th day after the operation. Compared with the monotherapy regimen of no liver protection treatment before the operation and receiving magnesium isoglycyrrhizinate injection 100mg once a day from the 1st to the 5th day after the operation.The efficacy and safety of treating postoperative liver function injury in patients undergoing laparoscopic hepatectomy for hepatocellular carcinoma were compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
96
Receiving 930mg of polyene phosphatidylcholine injection one day before the operation,twice a day. And 930mg of polyene phosphatidylcholine injection,twice a day, combined with 100mg of magnesium isoglycyrrhizinate injection once a day,from the 1st to the 5th day after the operation.
Receiving 100mg of magnesium isoglycyrrhizinate injection once a day,from the 1st to the 5th day after the operation.
Anhui Provincial Hospital
Hefei, Anhui, China
RECRUITINGThe average change of ALT on the 5th day after the operation
Time frame: The 5th day after the operation
The average change of ALT on the 1th day after the operation
Time frame: The 1th day after the operation
The average change of ALT on the 3th day after the operation
Time frame: The 3th day after the operation
The rate of ALT returning to normal on the 5th day after the operation
Time frame: The 5th day after the operation
The rate of AST returning to normal on the 5th day after the operation
Time frame: The 5th day after the operation
AEs
Time frame: Observation period 5 days after the operation
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