Erythropoietin - Albumin Platelet-rich Fibrin in Transcrestal Sinus Lifting With Simultaneous Implant Placement

Alexandria University20 enrolled

Overview

Background: Dental implant therapy in the posterior maxilla may be difficult owing to limited bone height after dental extraction with sinus pneumatization. Several approaches for sinus floor elevation have been documented, and hence trans crestal sinus lifting with albumin platelet rich plasma. Aim of the study: To compare between erythropoietin and albumin platelet rich fibrin transcrestal sinus lifting versus albumin platelet rich fibrin transcrestal sinus lifting using piezoelectric device in patients with atrophic maxilla. Methods: This study will be carried out as a randomized

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Sinus Lifting

Interventions

Erythropoietin and albumin PRF gel + implant placement

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Residual bone height not less than 5 mm measured from crestal bone to sinus floor. * Both genders. * Good oral hygiene * No previous surgery or radiation treatment on the maxillary sinus Exclusion Criteria: * Recent radiation therapy in maxilla. * Uncontrolled systemic diseases such as diabetes mellitus. * Heavy smoker (those who smoke ≥ 25 cigarettes a day). * Alcohol abuse. * Patient on anticoagulant drug * Severe allergic rhinitis. * Tumor or large cyst in the maxillary sinus. * Oroantral fistula. * Presence of acute or chronic sinus pathoses or sinus membrane perforation.(

Outcomes

Primary Outcomes

Change in pain scores

pain will be assessed through a 10 point visual analogue scale (VAS). (0-1=none, 2-4=mild, 5-7=moderate, 8-10=severe).

Time frame: up to 14 days

Change in edema

Edema will be assessed as follows: 1. None (no swelling) 2. Mild (intraoral swelling confined to the surgical field) 3. Moderate (extra oral swelling in the surgical zone) 4. Severe (extraoral swelling spreading beyond the surgical zone)

Time frame: up to 14 days

Change in implant stability

implant stability will be assessed using ostell device

Time frame: immediate and 4 months

Secondary Outcomes

Change in bone gain

amount of sinus bone gain (SBG) which equals implant protrusion length (IPL) added to Peri-implant sinus bone level (PSBL) which is the distance between the apex of the implant and sinus bone level

Time frame: baseline and 4 months

Change in bone density

it will be assessed using CBCT