The goal of this clinical trial is to determine if electrical brain stimulation applied to the front parts of the brain can help people who have had a stroke improve their fatigue, language, and attention. The main question it aims to answer is: * Does transcranial direct current stimulation (tDCS) administered to the pre-frontal areas of the brain improve post-stroke fatigue and aphasia? * What kinds of participant characteristics are associated with better improvement of post-stroke fatigue and aphasia? Researchers will compare active electrical stimulation to sham stimulation to see if the active stimulation does a better job at reducing fatigue and language deficits after stroke. Participants will be asked to complete fatigue, language, and cognitive testing before and after receiving 10 sessions of tDCS plus speech and language therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
60
The investigators will administer active tDCS to left dorsolateral prefrontal cortex (DLPFC) during 10 sessions of behavioral treatment. For active tDCS, the current will slowly be increased to 2mA and applied for 20 minutes.
This is a specific type of speech-language therapy that focuses on simultaneously improving auditory comprehension and behavioral attention. Participants will receive 10 sessions of this treatment.
This is a specific type of speech-language therapy that focuses on improving auditory comprehension . Participants will receive 10 sessions of this treatment.
The investigators will administer sham tDCS to left dorsolateral prefrontal cortex (DLPFC) during 10 sessions of behavioral treatment. For sham tDCS, the current will slowly be increased to 2mA over the course of 30 seconds and then immediately ramped back down to zero.
University of Michigan
Ann Arbor, Michigan, United States
NOT_YET_RECRUITINGSyracuse University
Syracuse, New York, United States
RECRUITINGFatigue Interference and Severity Scale for Aphasia (FISS-A)
Scale from 1-7, higher scores mean more significant fatigue
Time frame: baseline; within 1 week following the final treatment session; 3- month follow-up
Continuous Performance Test (CPT)
Time frame: baseline; within 1 week following the final treatment session; 3- month follow-up
Attention Network Test (ANT)
Time frame: baseline; within 1 week following the final treatment session; 3- month follow-up
Sentence comprehension task
Time frame: baseline; within 1 week following the final treatment session; 3- month follow-up
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