The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (multi-omic) and clinical data from patient cohorts through serial blood draws and the acquisition of leftover tissue and/or bone marrow aspirates during their routine therapy and disease monitoring. The primary goal is to understand the association between biomarkers and real-world clinical outcomes in these patient populations.
Study Type
OBSERVATIONAL
Enrollment
550
There are no interventions in this observational study.
The Center for Cancer and Blood Disorders
Bethesda, Maryland, United States
RECRUITINGCancer Care Specialists of Reno
Reno, Nevada, United States
RECRUITINGTaylor Cancer Research Center
Maumee, Ohio, United States
RECRUITINGTo assess biomarker landscape in the progression as well as baseline biospecimen samples and correlate with with real-world outcomes across multiple hematologic indications.
The goal of this biomarker discovery registry is to assess DNA and RNA expression patterns and potential biomarkers in biospecimens collected at baseline and throughout treatment, with the goal of generating hypotheses about predictive markers for therapy selection, prognostic indicators, and potential mechanisms of resistance to standard-of-care therapies across multiple hematologic indications.
Time frame: 5 years
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