Acute decompensated heart failure (ADHF) is a severe condition characterized by rapid deterioration of cardiac function, leading to impaired oxygen delivery and multi-organ dysfunction. ADHF often results in reduced physical and respiratory capacity, greater dependence on oxygen support, difficulty performing daily activities, and prolonged hospital stays. In recent years, early exercise-based cardiopulmonary rehabilitation (CPR) has been introduced as part of heart failure management. Evidence suggests that early CPR improves overall health and cardiac function in heart failure patients. However, data regarding its effects in ADHF remain limited. While some studies indicate that early CPR enhances physical function, its impact on respiratory parameters and clinical outcomes is less well established. Cardiopulmonary rehabilitation is a multidisciplinary program designed to promote physical, psychological, and social recovery in patients with cardiovascular and pulmonary diseases. It includes exercise training, education, psychosocial support, and behavioral strategies. Early CPR specifically aims to improve cardiovascular and respiratory functions in heart failure patients. Initiating CPR in the early phase of ADHF may accelerate recovery, strengthen cardiopulmonary function, shorten hospitalization, and improve quality of life. This study aims to evaluate the effects of early CPR on functional capacity, hemodynamic parameters, and respiratory parameters in patients with ADHF.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
An individualized CPR program including positioning, deep breathing exercises (diaphragmatic and segmental breathing exercises), pursed-lip breathing exercises, breathing exercises using incentive spirometry, and progressive mobilization exercises (in-bed range of motion exercises, sitting, standing, and walking exercises)
Routine in-hospital care for acute decompansated heart failure
Istanbul University- Cerrahpasa, Cardiology Institute
Istanbul, Turkey (Türkiye)
RECRUITINGFunctional capacity
It will be evaluated using 6-min walk test according to the guideline of American Thoracic Society
Time frame: At baseline and at hospital discharge, up to 14 days after admission
Physical performance
It will evaluated using Short Physical Performance Battery.
Time frame: At baseline and at hospital discharge, up to 14 days after admission
Maximum inspiratory and expiratory capacity
It will be evaluated using incentive spirometer.
Time frame: At baseline and at hospital discharge, up to 14 days after admission
Hemodynamic responses to exercise
The change in heart rate before and after exercise will be recorded
Time frame: At baseline and at hospital discharge, up to 14 days after admission
Hemodynamic responses to exercise
The change in blood pressure before and after exercise will be recorded
Time frame: At baseline and at hospital discharge, up to 14 days after admission
Hemodynamic responses to exercise
The change in oxygen saturation before and after exercise will be recorded
Time frame: At baseline and at hospital discharge, up to 14 days after admission
Subjective symptom responses to exercise
Subjective symptom responses to exercise will be evaluated by determining changes in the Modified Borg Dyspnea and Fatigue scales before and after exercise.
Time frame: At baseline and at hospital discharge, up to 14 days after admission
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