Surface EMG Testing on Swallowing in EoE Patients

Mayo Clinic30 enrolled

Overview

Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis

Evaluating surface electromyography (sEMG) assessment of swallowing and bolus preparation in patients with Eosinophilic Esophagitis (EoE).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Eosinophilic Esophagitis (EoE)

Interventions

Surface ElectromyographyDIAGNOSTIC_TEST

Tests performed to evaluate swallowing function

Fiberoptic Endoscopic Evaluation of SwallowingDIAGNOSTIC_TEST

Assessment of swallowing function

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Controls * Normal video swallow or score of 0 for dysphagia on ESSAI questionnaire * absence of dysphagia * age \>18 EoE participants * Documentation of EoE diagnosis by histologic criteria, * \>15 eos/hpf on most recent esophageal biopsy * age \>18 Exclusion Criteria: * Abnormal baseline video swallow * lack of MSK coordination to eat test meal * underlying neuromuscular disorder.

Locations (1)

Mayo Clinic

Rochester, Minnesota, United States

RECRUITING

Outcomes

Primary Outcomes

Preparatory phase time

Comparison of preparatory phase between cohorts

Time frame: Through study completion an average of 2 days

Secondary Outcomes

Time difference in swallow initiation

Time difference in swallow initiation between fiberoptic endoscopic evaluation of swallowing (FEES) vs sEMG

Time frame: Through study completion an average of 2 days

Central Contacts

Ryan Alexander, MD

CONTACT

507-284-4824 alexander.ryan2@mayo.edu

Mariah Robran, CCRP

CONTACT

507-266-3595 robran.mariah@mayo.edu

Data from ClinicalTrials.gov

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