Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic

aijun xu2,392 enrolled

Overview

The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional surgical risk associated with preoperative URTI symptoms. The main question it aims to answer is the appropriate timing of elective non-cardiac surgery in the post-COVID-19 era.

This study aims to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional surgical risk associated with preoperative URTI symptoms. The findings will provide evidence-based guidance for optimizing surgical timing decisions in the post-COVID-19 era.

Study Type

OBSERVATIONAL

Enrollment

2,392

Conditions

URTI Postoperative Complications COVID - 19 Elective Non-cardiac Surgery Perioperative Respiratory Adverse Events

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Aged 0-12 years * ASA physical status classification I-III * Undergoing non-cardiac surgery * Children presenting with mild URTI symptoms within 2 weeks before surgery Exclusion Criteria: * Presenting with severe underlying diseases (e.g., congenital heart disease, immunodeficiency) * Presenting with a single symptom of fever that can be explained by other diseases * Day surgery * Children with abnormal preoperative chest X-rays

Outcomes

Primary Outcomes

postoperative complications

The postoperative complications including hemorrhage, infection, gastrointestinal complications, respiratory adverse events (RAE), and recurrence of the primary disease.

Time frame: 7days

Secondary Outcomes

Intraoperative RAE

Intraoperative RAE, including hypercapnia, hypoxemia

Time frame: 1day

Emergence RAE

Emergence RAE, including hypercapnia, hypoxemia

Time frame: 1day

PACU stay

Meeting discharge criteria from PACU

Time frame: 1hour

Total hospital length of stay

Time frame: 10days

Postoperative length of stay

Postoperative hospital length of stay