The goal of this observational study is to evaluate Metabolic Health by fit analysis between calculated Nutrilite Metabolic Health Index and the result of Metabolomics analysis from blood plasma samples in healthy adult participants aged between 18 and 60 years. The main question it aims to answer: \- Does the Nutrilite Metabolic Health Index fit well with the result of Metabolomics analysis from blood plasma samples? 200 eligible participants will be enrolled in a single center, one site visit will be made to finish a health questionnaire, a lifestyle questionnaire, a routine physical checkup. Blood samples will be collected for routine blood test (blood sugar, total triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, uric acid), and for Metabolomics testing. Researchers will calculate the Nutrilite Metabolic Health Index based on participant data, and do the fit analysis against the result from Metabolomics analysis.
Study Type
OBSERVATIONAL
Enrollment
200
No intervention involved, participants will fill out some questionnaires and blood samples will drawn for test and analysis.
Shanghai MCC Hospital
Shanghai, Shanghai Municipality, China
Nutrilite Metabolic Health Index
Nutrilite Metabolic Health Index incorporates seven core biochemical parameters (see details in Secondary Outcome Measures): body mass index (BMI), waist circumference, fasting blood glucose (FBG) level, blood lipid profile (total cholesterol (TC), total triglycerides(TG), Low-Density Lipoprotein Cholesterol (LDL), High-Density Lipoprotein Cholesterol (HDL), blood pressure (Systolic Blood Pressure(SBP), and Diastolic Blood Pressure (BDP)), uric acid level, and history of fatty liver disease; along with four lifestyle and hereditary factors: smoking, alcohol consumption, age, and family history of metabolic diseases. After weighted calculation, the index score ranges from 0 to 100, divided into four grades: Excellent: 85-100 Moderate: 60-84 Poor: 40-59 Severe: 0-39
Time frame: day 1
SBP
SBP(Systolic Blood Pressure), ideally \<120 mmHg or still normal if less than 130mmHg
Time frame: day 1
DBP
BDP(Diastolic Blood Pressure), ideally \<80 mmHg, or still normal if less than 89 mmHg
Time frame: day 1
Blood test - LDL-C
LDL-C(Low-Density Lipoprotein Cholesterol) concentration level in the blood sample test: normal range 0-3.1mmol/L, higher than 3.1 mmol/L is abnormal;
Time frame: day 1
Blood test - HDL-C
HDL-C(High-Density Lipoprotein Cholesterol) concentration level in the blood sample test: normal range 1.04\~1.55 mmol/L, lower than 1.04 or higher than 1.55 mmol/L is abnormal;
Time frame: day 1
Blood test - TG
TG (Triglyceride) concentration level in the blood sample test : normal range 0\~1.7 mmol/L, higher than 1.7mmol/L is abnormal
Time frame: day 1
Blood test - TC
TC (Total Cholesterol) concentration level in the blood sample test: normal range 3-5.2 mmol/L; higher than 5.2 mmol/L is abnormal.
Time frame: day 1
Blood test - FBG
FBG(Fasting Blood Glucose) concentration level in the blood sample test: normal range 4.-5.5mmol/L, higher than 5.5 mmol/L is abnormal.
Time frame: day 1
BMI
BMI (Body Mass Index), BMI is calculated by weight/height\^2, where weight measured with unit kg, and height with unit meter, and weight and height will be combined to report BMI in kg/m\^2.
Time frame: day 1
Waist Circumference
waist circumference measured in cm (centimeter)
Time frame: day 1
Uric Acid Level
uric acid level in μmol/L, the normal range for adult male:149~416μmol/L, adult female:89~357μmol/L
Time frame: day 1
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