This is a Phase 1, single-center, randomized, placebo-controlled, ascending dose study. The study will evaluate the pharmacokinetics (PK), pharmacodynamic (PD), preliminary efficacy, safety and tolerability of BGM0504 following daily oral administrations in non-diabetic overweight or obese adult subjects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
Pharmaron CPC, Inc
Baltimore, Maryland, United States
RECRUITINGNumber of treatment adverse events
The relationship of each adverse event tothe investigational product was assessed by the investigator
Time frame: 11 weeks
Pharmacokinetic endpoint: Concentration of BGM0504 in plasma
Time frame: 11 weeks
Change in fasting weight at week 11
Time frame: 11 weeks
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Administered orally
Administered orally