This study evaluates the amount of nicotine, cannabis, and toxicants linked to the use of nicotine e-cigarette and/or cannabis products in the blood and urine of young adult users as well as the cannabis and nicotine use behaviors of consumers.
PRIMARY OBJECTIVE: I. To evaluate differences in self-reported nicotine and cannabis use behaviors and biomarkers of exposure to toxicants and carcinogens by product use status, to generate effect sizes required to calculate sample sizes needed for a larger study.
Study Type
OBSERVATIONAL
Enrollment
150
Subjects will asked which type of recruitment material they've seen when completing the screening survey
subjects will choose location when coordinator calls to schedule appointment
Self reported measure of current cannabis use that contains 30 questions assessing quantity, frequency of use and method of consumption in the past 30 days.
Roswell Park Comprehensive Cancer Center
Buffalo, New York, United States
RECRUITINGDifferences in biomarker levels across groups
Will compare the mean biomarker levels between groups using a one-way ANOVA model, with Bonferroni-adjusted pairwise comparisons, as appropriate.
Time frame: 1 study session lasting 1 hour
Differences in self reported nicotine and cannabis use behaviors
Self reported questionnaire
Time frame: 1 study session (1 hour)
Differences in psychosocial characteristics by group
Will be compared between groups using the appropriate general linear models. All model and test assumptions will be verified graphically, with transformations applied as appropriate.
Time frame: 1 study session (1 hour)
Study interest
Study interest and eligibility Measured via number of contacts to inquire about the study, and number of eligible applicants. The eligibility and interest rates of the individuals approached and the completion rates of the enrolled individuals will be estimated overall and by relevant factors (recruitment channel, type of advertisement) using 90% credible regions obtained by Jeffrey's prior method.
Time frame: Up to 1 year
Recall of study recruitment advertisement type
Analyses will be primarily descriptive to evaluate the reach and effectiveness of recruitment strategies. Key endpoints will be summarized overall and by relevant factors (ex., recruitment channel) using the appropriate descriptive statistics, with comparisons made using the Mann-Whitney U and Kruskal Wallis or Fisher's exact and Pearson chi-square tests, as appropriate.
Time frame: 1 study session (1 hour)
Recall of recruitment channel
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A 22-item questionnaire measuring e-cigarette dependence. Higher scores indicate greater dependence.
Will include where study information/advertisement was viewed. Analyses will be primarily descriptive to evaluate the reach and effectiveness of recruitment strategies. Key endpoints will be summarized overall and by relevant factors ex., recruitment channel) using the appropriate descriptive statistics.
Time frame: 1 study session (1 hour)
Completion method chosen by participants
On campus versus off-campus
Time frame: 1 study session (1 hour)