Predictive Value of CEA and ctDNA in Lung Cancer Recurrence

N/ANot Yet RecruitingNCT07170046

Guangdong Provincial People's Hospital100 enrolled

Overview

The study aims to investigate the predictive value of CEA levels for postoperative recurrence in the highly sensitive CEA lung cancer patients and to explore whether the dynamic changes of postoperative CEA and MRD in this population are related.This study was carried out to accurately predict the recurrence time, save the time and cost of changing the intervention strategy, and provide more personalized treatment for patients.

This study will collect two groups of cohorts: prospective and retrospective.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Lung Carcinoma

Eligibility

Sex: ALLMin age: 15 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Preoperative CEA \> 5mg/l 2. MRD testing was conducted before the operation 3. The primary lesion was resected through surgery 4. There should be at least two CEA and MRD follow-up tests within 2 years after the operation 5. Postoperative pathology confirmed it as a malignant lung tumor Exclusion Criteria: 1. Those without available imaging records 2. Patients with a history of malignant tumors within the past five years 3. Patients with secondary lung cancer

Outcomes

Primary Outcomes

Postoperative tumor recurrence or progression

If the tumor recurs or progresses within 2 years, it will be marked as 1. If not, it will be marked as 0.

Time frame: 2 years

Data from ClinicalTrials.gov

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