Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity in patients with macular dystrophy.
Macular dystrophies cause progressive central vision loss, but the relationship between structural retinal changes (OCT) and functional deficits (mf-ERG) with visual outcomes remains poorly understood. Current clinical assessment relies primarily on visual acuity, which inadequately reflects retinal damage or predicts disease progression. This knowledge gap limits prognostic accuracy and optimal patient management. Recent advances in OCT and mf-ERG technology provide an opportunity to establish robust structure-function correlations. Understanding these relationships will enhance patient care through improved prognosis, standardized monitoring protocols, and better clinical trial outcome measures for macular dystrophy patients.
Study Type
OBSERVATIONAL
Enrollment
30
retinal photography by OCT, VA measurement, and mfERG test
BCVA (best corrected visual acuity)
BCVA was recorded in 30 eyes of 30 patients with macular dystrophy.
Time frame: Day 1/month 3
CMT (central macular thickness) μm Central macular thickness measurement using optical coherence tomography
CMT (central macular thickness) in μm in 30 eyes of 30 patients with macular dystrophy Central macular thickness measurement using optical coherence tomography.
Time frame: Day1/month 3
mf-ERG amplituide nV/deg2
mf-ERG amplitude nV/deg² in 30 eyes of 30 patients with macular dystrophy multifocal electroretinogram amplitude measurement using the mf-ERG machine
Time frame: Day 1/month 6
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