Interdisciplinary Program to Improve Lifestyle in Chronic Pathology: Alt Pirineu Aran in Fit (APA-FIT)

Overview

Interdisciplinary Program to Improve the Lifestyle of Individuals with Chronic Conditions in the Alt Pirineu and Aran Region Sedentary behavior and lack of regular physical activity have been widely recognized as urgent global public health issues-not only because they are key risk factors for cardiovascular morbidity and mortality, but also due to their impact on major chronic diseases. Primary Objective / Hypothesis To evaluate the effectiveness of an intervention program aimed at improving the lifestyle of individuals with chronic conditions in the Alt Pirineu and Aran health region by promoting active living and physical activity (PA), healthy dietary habits, and positive mental health (PMH), through the use of a digital tool (APP). The program also aims to determine whether this intervention leads to a reduction in cardiovascular risk, comorbidity, and premature aging associated with non-communicable diseases. Study Design and Sample The sample will consist of individuals over 18 years of age with moderate to high cardiovascular risk who voluntarily participate in the project. The program will last for 9 months and will be structured into two groups: an intervention group, which will actively participate in the program through the APP, and a control group, which will not receive the intervention. Pre- and post-intervention measurements will be applied to assess the effects of the program. Applicability and Relevance This project seeks to implement an interdisciplinary care model for individuals with chronic conditions, aiming to enhance lifestyle behaviors, reduce comorbidity, and mitigate premature aging. The APA-fit digital tool seeks to implement this model by empowering patients in their self-care and facilitating seamless, effective communication between patients and healthcare professionals.

Project Justification: Lifestyle, Physical Activity and Public Health A sedentary lifestyle and lack of regular physical activity have been widely recognised as major global public health concerns. These behaviours are not only significant risk factors for cardiovascular morbidity and mortality, but are also strongly associated with the development and progression of chronic diseases such as cancer, obesity, and type 2 diabetes mellitus. According to the World Health Organization (WHO), physical inactivity accounts for 25% of breast and colon cancer cases, 27% of diabetes cases, and 30% of ischaemic heart disease cases. These figures underscore the urgent need for preventive and therapeutic interventions focused on promoting physical activity and healthy lifestyle habits. Globally, the prevalence of sedentary behaviour is estimated at 49.7%. A person is considered sedentary if they spend more than five hours seated per day and engage in less than 90 minutes of physical activity per week. Physical activity is defined as any bodily movement produced by skeletal muscles that results in a substantial increase in energy expenditure. This includes everyday activities such as walking, climbing stairs, performing household chores, or shopping. In contrast, exercise refers to planned, structured, and repetitive physical activity aimed at improving or maintaining physical fitness, health, and quality of life. The American College of Sports Medicine (ACSM) recommends that adults engage in moderate-intensity exercise for at least 30 minutes per day, five days per week, or vigorous-intensity exercise for 20 minutes per day, three days per week. Concurrently, dietary habits have deteriorated, particularly in developed countries, due to accelerated lifestyles, irregular meal patterns, and the widespread availability of ultra-processed foods. These changes have led to increased consumption of products high in sugars, saturated fats, and salt, and a decline in the intake of foods associated with healthy dietary patterns, such as the Mediterranean diet. This diet is characterised by a high intake of fruits, vegetables, legumes, nuts, whole grains, fish, and extra virgin olive oil, and a low intake of red and processed meats. The PREDIMED study has demonstrated that adherence to the Mediterranean diet significantly reduces the risk of cardiovascular events such as acute myocardial infarction and stroke. The combination of sedentary behaviour and poor dietary habits has contributed to a sustained rise in obesity prevalence, which has become one of the leading public health challenges. The WHO defines obesity as an abnormal or excessive accumulation of body fat that may impair health. It is diagnosed when the body mass index (BMI) is equal to or greater than 30 kg/m². In women, obesity is defined by a body fat percentage exceeding 35%, and in men, 30%. In Spain, the National Health Survey (2015) reported that 53.7% of adults were overweight or obese, and among children and adolescents (aged 2 to 17), the prevalence reached 27.8%. In Catalonia, the 2020 Health Survey indicated that 20% of the adult population was sedentary, rising to 38.1% when minimally active individuals were included. Furthermore, 33.7% of individuals over the age of 15 were overweight, and 17% were obese, with a clear upward trend. Scientific literature has also established a link between obesity, sedentary behaviour, and psycho-emotional disorders such as depression and anxiety. These conditions may act both as risk factors and consequences of unhealthy lifestyles, creating a vicious cycle that is difficult to break. Several studies have shown that multidisciplinary interventions combining physical exercise, nutritional education, and behavioural support can significantly improve the physical and emotional health of individuals with obesity, reducing comorbidities and the need for pharmacological or invasive treatments such as bariatric surgery. There is robust scientific evidence supporting the benefits of regular moderate physical activity and healthy eating habits. Physically, these practices help reduce the risk of cardiovascular disease, hypertension, type 2 diabetes, and other metabolic disorders. Psychologically, they promote autonomy, self-esteem, regulation of sleep-wake cycles, and a reduction in anxiety and depression symptoms. In response to this public health challenge, various initiatives and intervention programmes have been developed at international, national, and regional levels. At the European level, the EUPAP (European Physical Activity on Prescription) programme, led by the Swedish Public Health Agency and the Swedish Association of Physical Activity Professionals, promotes physical activity prescription as a tool to improve health, prevent non-communicable diseases, and reduce health inequalities. The Swedish model is currently being adapted and implemented in several European regions, including Catalonia, where the \*Caminem\* project has been active since 2012. In Spain, the NAOS Strategy (Nutrition, Physical Activity and Obesity Prevention) promotes physical activity in schools, educational institutions, and workplaces, as well as a balanced diet based on the Mediterranean pattern. In Catalonia, the PAAS (Comprehensive Plan for the Promotion of Health through Physical Activity and Healthy Eating), developed by the Department of Health, coordinates actions across five domains: education, healthcare, community, workplace, and communication. This plan aligns with the WHO's global strategy and the NAOS framework established by the Spanish Agency for Consumer Affairs, Food Safety and Nutrition. This context highlights the need to develop and evaluate new interdisciplinary intervention programmes that integrate physical activity, nutritional education, and emotional support as central components for health promotion and chronic disease prevention. These programmes must be adaptable to diverse contexts and population groups, particularly in regions with specific geographical and socioeconomic characteristics, such as mountainous or rural areas. The proposed project is framed within this strategic approach and aims to improve the health and quality of life of the population by promoting an active and healthy lifestyle. Through a structured, evidence-based intervention, the project seeks to reduce the prevalence of sedentary behaviour, obesity, and associated disorders, while enhancing emotional well-being and social cohesion. Rigorous evaluation of outcomes will generate transferable knowledge and contribute to the development of more effective and sustainable public health policies. Methodology This study employs a two-phase quantitative design: 1. Phase I: A cross-sectional, descriptive observational study of a sample of 520 participants. 2. Phase II: A randomized controlled trial with two arms (intervention vs. control), stratified by high versus moderate cardiovascular risk, using a pre-post test model. The study will be conducted across eight primary care areas in the Alt Pirineu and Aran region, with sample sizes allocated according to local population density. The nine-month interdisciplinary intervention comprises three core strategies: * Physical Activity Prescription * Healthy Nutritional Habits * Positive Mental Health Monitoring and follow-up will be performed via the APA-fit app-web platform. Assessment tools include: * Physical Activity \& Fitness: International Physical Activity Questionnaire; Rapid Physical Activity Classifier; 6-minute walk test; graded exercise test * Nutrition: Mediterranean Diet Adherence Screener; Food Frequency Questionnaire * Body Composition \& Metabolic/Cardiovascular Risk: Advanced anthropometry; bioelectrical impedance analysis * Psychosocial Health: Positive Mental Health Questionnaire * General Health: Lipid and glucose blood profile; evaluation of toxic habits; clinical history